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Acute renal failure following collective intoxication by Cortinarius orellanus

Twenty-six young men with no previous medical history all ingested mushroom soup, exclusively made with Cortinarius orellanus. They were hospitalized 10-12 days after the incident. On admission, 12 patients presented with acute tubulointerstitial nephritis with acute renal failure; 8 required haemod...

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Bibliographic Details
Published in:Intensive care medicine 1990-01, Vol.16 (8), p.506-510
Main Authors: BOUGET, J, BOUSSER, J, PATS, B, RAMEE, M.-P, CHEVET, D, RIFLE, G, GIUDICELLI, C.-P, THOMAS, R
Format: Article
Language:English
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Summary:Twenty-six young men with no previous medical history all ingested mushroom soup, exclusively made with Cortinarius orellanus. They were hospitalized 10-12 days after the incident. On admission, 12 patients presented with acute tubulointerstitial nephritis with acute renal failure; 8 required haemodialysis. In addition to symptomatic treatment, 9 patients were given corticosteroids. In this group of 12 patients, 8 recovered rapidly, and the other 4 suffered from chronic renal failure for several months. In the other group of 14 patients, initial leukocyturia was observed in 12 cases, although renal function remained normal during a one-year follow-up. Hepatic acetylation and hydroxylation tests performed after 6 months in 22 patients did not provide any explanation for the strong individual sensitivity to the renal toxicity of this fungus.
ISSN:0342-4642
1432-1238
DOI:10.1007/BF01709401