Angioinvasion by neuroendocrine jejunal tumor. Demonstration of a malignancy sign by acetone compression

Neuroendocrine neoplasms of the digestive system are classified by current World Health Organization (WHO) guidelines as G1 and G2 neuroendocrine tumors (NET) as well as neuroendocrine carcinoma (NEC) based on proliferation and differentiation. The G1 NET tumors are highly differentiated, low prolif...

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Bibliographic Details
Published in:Der Pathologe 2013-07, Vol.34 (4), p.352
Main Authors: Scheel, A H, Kitz, J, Heimbucher, J, Ströbel, P, Rüschoff, J
Format: Article
Language:ger
Subjects:
Adipose Tissue - blood supply
Adipose Tissue - pathology
Aged
Cell Proliferation
Humans
Ileus - pathology
Ileus - surgery
Jejunal Neoplasms - pathology
Jejunal Neoplasms - surgery
Jejunum - blood supply
Jejunum - pathology
Jejunum - surgery
Male
Mesenteric Veins - pathology
Mesenteric Veins - surgery
Neoplasm Invasiveness
Neoplasm Staging
Neuroendocrine Tumors - pathology
Neuroendocrine Tumors - surgery
Prognosis
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Description
Summary:Neuroendocrine neoplasms of the digestive system are classified by current World Health Organization (WHO) guidelines as G1 and G2 neuroendocrine tumors (NET) as well as neuroendocrine carcinoma (NEC) based on proliferation and differentiation. The G1 NET tumors are highly differentiated, low proliferating and usually exhibit a favorable course of the disease without the development of metastases. In the case presented here, angioinvasion by a pT3 NET G1 was demonstrated after complete work-up of the mesenterial fat by acetone compression. The findings indicate an unfavorable course of disease requiring intensive surveillance.
ISSN:1432-1963
DOI:10.1007/s00292-012-1737-y