Identification of Cell-Penetrating Peptides That Are Bactericidal to Neisseria meningitidis and Prevent Inflammatory Responses upon Infection

• Published in: Antimicrobial Agents and Chemotherapy 2013-08, Vol.57 (8), p.3704-3712
• Main Authors: ERIKSSON, Olaspers Sara, GEÖRG, Miriam, SJÖLINDER, Hong, SILLARD, Rannar, LINDBERG, Staffan, LANGEL, Ülo, JONSSON, Ann-Beth
• Format: Article
• Language: English
• Subjects: Animals; Anti-Bacterial Agents - chemical synthesis; Anti-Bacterial Agents - pharmacology; Anti-Inflammatory Agents - immunology; Anti-Inflammatory Agents - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antimicrobial Cationic Peptides - chemical synthesis; Antimicrobial Cationic Peptides - isolation & purification; Antimicrobial Cationic Peptides - pharmacology; Bacteria; Bacterial diseases; Bacterial diseases of the nervous system. Bacterial myositis; Biological and medical sciences; Cell Membrane; Cell-Penetrating Peptides; Cell-Penetrating Peptides - chemical synthesis; Cell-Penetrating Peptides - isolation & purification; Cell-Penetrating Peptides - pharmacology; Cytokines - immunology; Drug Evaluation, Preclinical; Experimental Therapeutics; Galanin; Galanin - immunology; Galanin - pharmacology; Human bacterial diseases; Humans; Infectious diseases; Inflammation; Inflammation - drug therapy; Lipopolysaccharides - immunology; Lipopolysaccharides - pharmacology; Macrophages - drug effects; Macrophages - immunology; Medical sciences; Membrane Cofactor Protein - genetics; Membrane Cofactor Protein - metabolism; Meningococcal Infections - drug therapy; Mice; Mice, Transgenic; Neisseria meningitidis; Neisseria meningitidis - drug effects; Pharmacology. Drug treatments; Recombinant Fusion Proteins; Recombinant Fusion Proteins - immunology; Recombinant Fusion Proteins - pharmacology; Wasp Venoms; Wasp Venoms - immunology; Wasp Venoms - pharmacology
• ISSN: 0066-4804; 1098-6596; 1098-6596
• DOI: 10.1128/AAC.00624-13

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