A comparison of conventional surfactant treatment and partial liquid ventilation on the lung volume of injured ventilated small lungs

As an alternative to surfactant therapy (ST), partial liquid ventilation (PLV) with perfluorocarbons (PFC) has been considered as a treatment for acute lung injury (ALI) in newborns. The instilled PFC is much heavier than the instilled surfactant and the aim of this study was to investigate whether...

Full description

Saved in:
Bibliographic Details
Published in:Physiological measurement 2013-08, Vol.34 (8), p.915-924
Main Authors: Proquitté, Hans, Hartenstein, Sebastian, Koelsch, Uwe, Wauer, Roland R, Rüdiger, Mario, Schmalisch, Gerd
Format: Article
Language:English
Subjects:
animal
Animals
Body Weight
Liquid Ventilation
Lung Injury - drug therapy
Lung Injury - physiopathology
Lung Volume Measurements
mechanical ventilation
neonate
perfluorocarbon
Pulmonary Surfactants - therapeutic use
Respiration, Artificial
surfactant
Sus scrofa
total lung volume
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:As an alternative to surfactant therapy (ST), partial liquid ventilation (PLV) with perfluorocarbons (PFC) has been considered as a treatment for acute lung injury (ALI) in newborns. The instilled PFC is much heavier than the instilled surfactant and the aim of this study was to investigate whether PLV, compared to ST, increases the end-expiratory volume of the lung (VL). Fifteen newborn piglets (age
ISSN:0967-3334
1361-6579
DOI:10.1088/0967-3334/34/8/915