Adsorption of a PEO-PPO-PEO triblock copolymer on metal oxide surfaces with a view to reducing protein adsorption and further biofouling

Biomolecule adsorption is the first stage of biofouling. The aim of this work was to reduce the adsorption of proteins on stainless steel (SS) and titanium surfaces by modifying them with a poly(ethylene oxide) (PEO)-poly(propylene oxide) (PPO)-PEO triblock copolymer. Anchoring of the central PPO bl...

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Bibliographic Details
Published in:Biofouling (Chur, Switzerland) Switzerland), 2013-10, Vol.29 (9), p.1123-1137
Main Authors: Yang, Y., Poleunis, C., Románszki, L., Telegdi, J., Dupont-Gillain, C.C.
Format: Article
Language:English
Subjects:
Adsorption
Animals
biofouling
Biofouling - prevention & control
Cattle
Cytochromes c - metabolism
Fibrinogen - metabolism
Horses
Humans
Hydrophobic and Hydrophilic Interactions
Mass Spectrometry
metal oxide
PEO-PPO-PEO
Phosphorous Acids - chemistry
Photoelectron Spectroscopy
Polyethylene Glycols - chemistry
Propylene Glycols - chemistry
protein adsorption
quartz crystal microbalance (QCM)
Quartz Crystal Microbalance Techniques
Serum Albumin, Bovine - metabolism
Stainless Steel - chemistry
surface modification
Titanium - chemistry
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Summary:Biomolecule adsorption is the first stage of biofouling. The aim of this work was to reduce the adsorption of proteins on stainless steel (SS) and titanium surfaces by modifying them with a poly(ethylene oxide) (PEO)-poly(propylene oxide) (PPO)-PEO triblock copolymer. Anchoring of the central PPO block of the copolymer is known to be favoured by hydrophobic interaction with the substratum. Therefore, the surfaces of metal oxides were first modified by self-assembly of octadecylphosphonic acid. PEO-PPO-PEO preadsorbed on the hydrophobized surfaces of titanium or SS was shown to prevent the adsorption of bovine serum albumin (BSA), fibrinogen and cytochrome C, as monitored by quartz crystal microbalance (QCM). Moreover, X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry were used to characterize the surfaces of the SS and titanium after competitive adsorption of PEO-PPO-PEO and BSA. The results show that the adsorption of BSA is well prevented on hydrophobized surfaces, in contrast to the surfaces of native metal oxides.
ISSN:0892-7014
1029-2454
DOI:10.1080/08927014.2013.830109