Relationship between time of day and periprocedural myocardial infarction after elective angioplasty

Objectives: To test if the time of day significantly influences the occurrence of type 4A myocardial infarction in elective patients undergoing percutaneous coronary intervention (PCI). Background: Recent studies have suggested an influence of circadian rhythms on myocardial infarction size and mort...

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Bibliographic Details
Published in:Chronobiology international 2014-03, Vol.31 (2), p.206-213
Main Authors: Fournier, Stephane, Puricel, Serban, Morawiec, Beata, Eeckhout, Eric, Mangiacapra, Fabio, Trana, Catalina, Tapponnier, Maxime, Iglesias, Juan F., Michiels, Vincent, Stauffer, Jean-Christophe, Beggah, Ahmed, Monney, Pierre, Gobet, Stéphanie, Vogt, Pierre, Cook, Stéphane, Muller, Olivier
Format: Article
Language:English
Subjects:
Aged
Angioplasty, Balloon, Coronary - adverse effects
Appointments and Schedules
Chi-Square Distribution
Circadian Rhythm
Female
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction - diagnosis
Myocardial Infarction - etiology
Myocardial Infarction - physiopathology
Odds Ratio
percutaneous coronary intervention
periprocedural myocardial infarction
Propensity Score
Retrospective Studies
Risk Factors
Switzerland
Time Factors
Treatment Outcome
type 4A myocardial infarction
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Summary:Objectives: To test if the time of day significantly influences the occurrence of type 4A myocardial infarction in elective patients undergoing percutaneous coronary intervention (PCI). Background: Recent studies have suggested an influence of circadian rhythms on myocardial infarction size and mortality among patients with ST-elevation myocardial infarction. The aim of the study is to investigate whether periprocedural myocardial infarction (PMI) is influenced by the time of day in elective patients undergoing PCI. Methods: All consecutive patients undergoing elective PCI between 2007 and 2011 at our institutions with known post-interventional troponin were retrospectively included. Patients (n = 1021) were divided into two groups according to the starting time of the PCI: the morning group (n = 651) between 07:00 and 11:59, and the afternoon group (n = 370) between 12:00 and 18:59. Baseline and procedural characteristics as well as clinical outcome defined as the occurrence of PMI were compared between groups. In order to limit selection bias, all analyses were equally performed in 308 pairs using propensity score (PS) matching. Results: In the overall population, the rate of PMI was statistically lower in the morning group compared to the afternoon group (20% vs. 30%, p 
ISSN:0742-0528
1525-6073
DOI:10.3109/07420528.2013.839561