Atypical femoral fractures in bisphosphonate therapy

Bisphosphonates (BP) play an important role in the therapy of osteoporosis as they effectively reduce the risk of fractures. Atypical femoral fractures (AFF) have recently been described as an adverse effect of BP treatment. We present 3 women under therapy with BP, who had five AFF, among these thr...

Full description

Saved in:
Bibliographic Details
Published in:Der Unfallchirurg 2015-01, Vol.118 (1), p.88
Main Authors: Ballaschk, A, Kalaitzis, N, Röpke, M, Piatek, S
Format: Article
Language:ger
Subjects:
Aged
Aged, 80 and over
Bone Density Conservation Agents - adverse effects
Diphosphonates - adverse effects
Female
Femoral Fractures - chemically induced
Femoral Fractures - diagnosis
Femoral Fractures - surgery
Fractures, Stress - chemically induced
Fractures, Stress - diagnosis
Fractures, Stress - surgery
Humans
Male
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Bisphosphonates (BP) play an important role in the therapy of osteoporosis as they effectively reduce the risk of fractures. Atypical femoral fractures (AFF) have recently been described as an adverse effect of BP treatment. We present 3 women under therapy with BP, who had five AFF, among these three complete and two incomplete fractures. The incidence of AFF under therapy with BP is low, and the benefit regarding reduction of spinal fractures and fractures of the proximal femur is much higher than the risk for an AFF.
ISSN:1433-044X
DOI:10.1007/s00113-013-2526-7