Cognitive Behaviour Therapy to Improve Mood in People with Epilepsy: A Randomised Controlled Trial

This study compared a 9-week individualised Cognitive Behaviour Therapy (CBT) programme for people with epilepsy (PWE), with a wait-list control. Fifty-nine PWE were randomised and 45 (75%) completed post-treatment outcomes. People with lower quality of life (QoL), particularly for cognitive functio...

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Bibliographic Details
Published in:Cognitive behaviour therapy 2014-04, Vol.43 (2), p.153-166
Main Authors: Gandy, Milena, Sharpe, Louise, Nicholson Perry, Kathryn, Thayer, Zoe, Miller, Laurie, Boserio, Janet, Mohamed, Armin
Format: Article
Language:English
Subjects:
Adult
Affect
Aged
anxiety
Anxiety - complications
Anxiety - psychology
Anxiety - therapy
Cognitive therapy
Cognitive Therapy - methods
Depression - complications
Depression - psychology
Depression - therapy
Epilepsy
Epilepsy - complications
Epilepsy - psychology
Female
Humans
Male
Mental depression
Mental health care
Middle Aged
mood
psychopathology
psychotherapy
Quality of Life
Suicidal Ideation
Treatment Outcome
Young Adult
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Summary:This study compared a 9-week individualised Cognitive Behaviour Therapy (CBT) programme for people with epilepsy (PWE), with a wait-list control. Fifty-nine PWE were randomised and 45 (75%) completed post-treatment outcomes. People with lower quality of life (QoL), particularly for cognitive functioning, were more likely to drop out. Analyses based on treatment completers demonstrated significant improvements on the Neurological Depressive Disorders Inventory for Epilepsy (p = .045) and Hospital Anxiety Depression Scale-Depression subscale (p = .048). Importantly, CBT significantly reduced the likelihood of clinical depressive symptoms (p = .014) and suicidal ideation (p = .005). Improvements were not observed for anxiety, QoL or maintained overtime for depression. Results suggest that CBT was effective, however, and could be improved to increase patient retention and long-term outcomes.
ISSN:1650-6073
1651-2316
DOI:10.1080/16506073.2014.892530