Factors Underlying Restricted Crossover Localization in Barley Meiosis

Meiotic recombination results in the formation of cytological structures known as chiasmata at the sites of genetic crossovers (COs). The formation of at least one chiasma/CO between homologous chromosome pairs is essential for accurate chromosome segregation at the first meiotic division as well as...

Full description

Saved in:
Bibliographic Details
Published in:Annual review of genetics 2014-01, Vol.48 (1), p.29-47
Main Authors: Higgins, James D, Osman, Kim, Jones, Gareth H, Franklin, F. Chris H
Format: Article
Language:English
Subjects:
Barley
Biological variation
Cell Cycle - genetics
cereals
chiasma
Chromosome Segregation - genetics
chromosome synapsis
Chromosomes
Crossing Over, Genetic
Deoxyribonucleic acid
DNA
DNA Breaks, Double-Stranded
Genetic diversity
Grasses
Homologous Recombination - genetics
Hordeum - genetics
Hordeum vulgare
Meiosis - genetics
Plant breeding
poaceae
recombination
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Meiotic recombination results in the formation of cytological structures known as chiasmata at the sites of genetic crossovers (COs). The formation of at least one chiasma/CO between homologous chromosome pairs is essential for accurate chromosome segregation at the first meiotic division as well as for generating genetic variation. Although DNA double-strand breaks, which initiate recombination, are widely distributed along the chromosomes, this is not necessarily reflected in the chiasma distribution. In many species there is a tendency for chiasmata to be distributed in favored regions along the chromosomes, whereas in others, such as barley and some other grasses, chiasma localization is extremely pronounced. Localization of chiasma to the distal regions of barley chromosomes restricts the genetic variation available to breeders. Studies reviewed herein are beginning to provide an explanation for chiasma localization in barley. Moreover, they suggest a potential route to manipulating chiasma distribution that could be of value to plant breeders.
ISSN:0066-4197
1545-2948
DOI:10.1146/annurev-genet-120213-092509