Modulatory role of Acacia honey from north-west Nigeria on sodium arsenite-induced clastogenicity and oxidative stress in male Wistar rats

Effect of Acacia honey from north-west Nigeria on sodium arsenite-induced oxidative damage and clastogenicity in male Wistar rats was investigated. Animals were divided into four groups and were treated daily via oral gavage for one week before they were sacrificed. Brain, liver and blood serum were...

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Bibliographic Details
Published in:Natural product research 2015-02, Vol.29 (4), p.321-326
Main Authors: Muhammad, Aliyu, Odunola, Oyeronke A., Gbadegesin, Michael A., Adegoke, Ayodeji M., Olugbami, J. Olorunjuwon, Uche, Ndidi S.
Format: Article
Language:English
Subjects:
Acacia
Acacia honey
Animals
Antioxidants - pharmacology
Arsenites - toxicity
clastogen
Honey
Male
Mutagens
Nigeria
oxidative damage
Oxidative Stress
Rats, Wistar
sodium arsenite
Sodium Compounds - toxicity
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Summary:Effect of Acacia honey from north-west Nigeria on sodium arsenite-induced oxidative damage and clastogenicity in male Wistar rats was investigated. Animals were divided into four groups and were treated daily via oral gavage for one week before they were sacrificed. Brain, liver and blood serum were collected for antioxidant and protein assays. Clastogenicity, in vitro antioxidant activity, vitamins and minerals were also evaluated. From the results, co-administration of Acacia honey with sodium arsenite on the animals increased (P 
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2014.940945