Role of (99m)Tc-MDP bone scan in the diagnosis of Erdheim-Chester disease

Erdheim-Chester disease (ECD) is a rare systemic non-Langerhans cell histiocytosis. It is a progressive disease of unknown etiology. The (99m)technetium-methylene diphosphonate ((99m)Tc-MDP) bone scan is useful in finding the sites of involvement in the skeleton and is helpful in excluding other cau...

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Bibliographic Details
Published in:Indian journal of nuclear medicine 2014-07, Vol.29 (3), p.165
Main Authors: Mukherjee, Anirban, Damle, Nishikant, Bal, Chandrasekhar, Arora, Arundeep, Singhal, Abhinav, Tripathi, Madhavi, Peepre, Karan
Format: Article
Language:English
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Summary:Erdheim-Chester disease (ECD) is a rare systemic non-Langerhans cell histiocytosis. It is a progressive disease of unknown etiology. The (99m)technetium-methylene diphosphonate ((99m)Tc-MDP) bone scan is useful in finding the sites of involvement in the skeleton and is helpful in excluding other causes of bony pain. Also a scintigraphic pattern consistent with ECD should alert the physician to evaluate the patient for visceral sites of involvement using fludeoxyglucose positron emission tomography/computed tomography (FDG PET/CT), as this is known to be fatal at times.
ISSN:0972-3919
DOI:10.4103/0972-3919.136575