A second case of white lentiginosis

White lentiginosis is characterized by white guttate macules with a typical histological structure: lentiginosis hyperplasia with hypopigmentation. A 23-year-old woman, from Algeria, presented with white macules from 5 years ago. Few women in her family had the same trouble. Cutaneous examination re...

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Bibliographic Details
Published in:Annales de dermatologie et de vénéréologie 2015-04, Vol.142 (4), p.281
Main Authors: Moulinas, C, Banea, S, De Cambourg, G, Bochaton, H, Tortel, M-C, Cribier, B, Mahé, A
Format: Article
Language:fre
Subjects:
Algeria - ethnology
Diagnosis, Differential
Female
Humans
Hypopigmentation - diagnosis
Hypopigmentation - genetics
Hypopigmentation - pathology
Lentigo - diagnosis
Lentigo - genetics
Lentigo - pathology
Skin Pigmentation
Young Adult
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Summary:White lentiginosis is characterized by white guttate macules with a typical histological structure: lentiginosis hyperplasia with hypopigmentation. A 23-year-old woman, from Algeria, presented with white macules from 5 years ago. Few women in her family had the same trouble. Cutaneous examination revealed diffused white little macules. Histological examination showed a lentiginous hyperplasia of the epidermis, with elongated club-shaped rete ridges and an unusual loss of pigmentation. Different diagnosis should be discussed with disseminated leucoderma macules. Nevertheless, the only one which corresponds with our case is the white lentiginosis. To our knowledge, it is the first case described since Grosshans et al. in 1994. Our patient is a descendant of the original case's family. This new case appears to confirm the genetic origin of the disorder and suggests autosomal dominant or X-linked inheritance.
ISSN:0151-9638
DOI:10.1016/j.annder.2015.01.017