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new pregnane glycoside from Gomphocarpus fruticosus growing in Egypt

Phytochemical investigation of Gomphocarpus fruticosus (L.) Ait. of Egyptian origin afforded the new pregnane glycoside lineolon-3-O-[ β -D-oleandropyranosyl-(1–4)- β -D-cymaropyranosyl-(1–4)- β -D-cymaropyranoside], along with six known compounds. The structures of the isolated compounds were eluci...

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Published in:	Natural product research 2016-05, Vol.30 (9), p.1060-1067
Main Authors:	Marzouk, Amani M, Osman, Samir M, Gohar, Ahmed A
Format:	Article
Language:	English
Subjects:	acetates Apocynaceae Apocynaceae - chemistry Asclepiadoideae betulinic acid cardenolides Egypt glycosides Glycosides - analysis Glycosides - isolation & purification Gomphocarpus fruticosus gomphofruticososide Magnetic Resonance Spectroscopy Mass Spectrometry Molecular Structure nuclear magnetic resonance spectroscopy Plant Extracts - analysis pregnane glycosides Pregnanes - analysis Pregnanes - isolation & purification spectral analysis triterpenoids
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creator	Marzouk, Amani M Osman, Samir M Gohar, Ahmed A
description	Phytochemical investigation of Gomphocarpus fruticosus (L.) Ait. of Egyptian origin afforded the new pregnane glycoside lineolon-3-O-[ β -D-oleandropyranosyl-(1–4)- β -D-cymaropyranosyl-(1–4)- β -D-cymaropyranoside], along with six known compounds. The structures of the isolated compounds were elucidated on the basis of extensive spectroscopic evidences derived from 1D, 2D NMR experiments, mass spectrometry and by comparing their physical and spectroscopic data to literature. These included the triterpenoids 3 β -taraxerol, 3 β -taraxerol acetate and betulinic acid, which are identified for the first time in G . fruticosus and the cardenolides uzarigenin, gomphoside and calotropin.
doi_str_mv	10.1080/14786419.2015.1107059
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subjects	acetates Apocynaceae Apocynaceae - chemistry Asclepiadoideae betulinic acid cardenolides Egypt glycosides Glycosides - analysis Glycosides - isolation & purification Gomphocarpus fruticosus gomphofruticososide Magnetic Resonance Spectroscopy Mass Spectrometry Molecular Structure nuclear magnetic resonance spectroscopy Plant Extracts - analysis pregnane glycosides Pregnanes - analysis Pregnanes - isolation & purification spectral analysis triterpenoids
title	new pregnane glycoside from Gomphocarpus fruticosus growing in Egypt
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