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Homocysteine in embryo culture media as a predictor of pregnancy outcome in assisted reproductive technology

The aim of this study was to determine whether homocysteine (hcy) concentrations in embryo culture media correlate with pregnancy outcome in assisted reproductive technology (ART) cycles. Forty patients who underwent single embryo transfer at the infertility clinic of a tertiary care center were rec...

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Bibliographic Details
Published in:Gynecological endocrinology 2016-03, Vol.32 (3), p.193-195
Main Authors: Boyama, Burcu Aydin, Cepni, Ismail, Imamoglu, Metehan, Oncul, Mahmut, Tuten, Abdullah, Yuksel, Mehmet Aytac, Kervancioglu, Mehmet Ertan, Kaleli, Semih, Ocal, Pelin
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Language:English
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Summary:The aim of this study was to determine whether homocysteine (hcy) concentrations in embryo culture media correlate with pregnancy outcome in assisted reproductive technology (ART) cycles. Forty patients who underwent single embryo transfer at the infertility clinic of a tertiary care center were recruited for this case-control study. Spent embryo culture media from all patients were collected after single embryo transfer on day 3 (n = 40). Hcy concentrations in embryo culture media were analyzed by enzyme cycling method. Patients were grouped according to the diagnosis of a clinical pregnancy. Sixteen patients were pregnant while 24 patients failed to achieve conception. Mean Hcy levels in the culture media were significantly different between the groups (p 
ISSN:0951-3590
1473-0766
DOI:10.3109/09513590.2015.1102877