Use of an optical clearing agent to enhance the visibility of subsurface structures and lesions from tooth occlusal surfaces

The purpose of this study is to show that optical clearing agents can be used to increase the visibility of deeply penetrating occlusal lesions that have reached the underlying dentin and spread laterally under the enamel. Previous studies have shown that high refractive index fluids can increase th...

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Bibliographic Details
Published in:Journal of biomedical optics 2016-08, Vol.21 (8), p.081206-081206
Main Authors: Kang, Hobin, Darling, Cynthia L, Fried, Daniel
Format: Article
Language:English
Subjects:
Dental Enamel - diagnostic imaging
Dental Enamel - pathology
Dentin - diagnostic imaging
Dentin - pathology
Humans
Image Processing, Computer-Assisted - methods
Microradiography
Polyvinyls - chemistry
Siloxanes - chemistry
Special Section on Tissue and Blood Optical Clearing for Biomedical Applications
Tomography, Optical Coherence - methods
Tooth - diagnostic imaging
Tooth - pathology
Tooth Demineralization - diagnostic imaging
Tooth Demineralization - pathology
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Summary:The purpose of this study is to show that optical clearing agents can be used to increase the visibility of deeply penetrating occlusal lesions that have reached the underlying dentin and spread laterally under the enamel. Previous studies have shown that high refractive index fluids can increase the contrast of caries lesions. Extracted teeth with natural occlusal lesions were imaged with optical coherence tomography (OCT) with and without the addition of a transparent vinyl polysiloxane impression material (VPS) currently used in vivo. The relative intensity of the reflectivity from the underlying lesion area for each sample was measured before and after application of the VPS. Lesion presence was confirmed with polarized light microscopy and microradiography. Application of VPS significantly increased (P
ISSN:1083-3668
1560-2281
DOI:10.1117/1.JBO.21.8.081206