Does ovulation induction and intrauterine insemination affect perinatal outcomes in singletons?

• Published in: The journal of maternal-fetal & neonatal medicine 2018-01, Vol.31 (1), p.14-17
• Main Authors: Yılmaz, Nafiye Karakaş, Sargın, Ayla, Erkılınç, Selçuk, Özer, İrfan, Engin-Üstün, Yaprak
• Format: Article
• Language: English
• Subjects: Female; Humans; Infant, Newborn; Insemination, Artificial - adverse effects; Intrauterine insemination; Ovulation Induction - adverse effects; perinatal outcomes; Pregnancy; Pregnancy Complications - epidemiology; Pregnancy Complications - etiology; Pregnancy Outcome - epidemiology; Retrospective Studies; singletons; Turkey - epidemiology; Young Adult
• ISSN: 1476-7058; 1476-4954
• DOI: 10.1080/14767058.2016.1223033

Aim: To evaluate the effect of solely intrauterine insemination on perinatal outcomes. Methods: A total of 3830 OI/IUI cycles between January 2007 and December 2012 were included in the study. Three hundred and fifty-eight pregnancies following intrauterine insemination were encountered during the study period. Data from 246 pregnancies conceived through OI/IUI treatment were available. A total of 438 singletons with no maternal risk constituted the control group. The two groups were compared according to perinatal outcomes. Results: There was a statistically significant difference between the groups in first trimester abortion and intrauterine demise. At least one or more perinatal adverse outcomes occurred in study and control groups with the rates of 38.4% and 18.5%, respectively. There were significant differences in preterm delivery rate and oligohydramnios between the groups. There were also significant differences in the rate of neonates with a birth weight