Intestinal Bacterial Infection Diagnosed by Histological Examination of Endoscopic Biopsy Specimens

Intestinal spirochetosis (IS) in humans is characterized by spirochetal microorganisms attached to the luminal surface of the colonic epithelium. In the present case, attached organisms appeared as 3- to 4 μm-thick (average thickness, 3.4 μm) basophilic fringes or haze in HE-stained endoscopic biops...

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Bibliographic Details
Published in:Case reports in gastroenterology 2016-10, Vol.10 (3), p.629-632
Main Authors: Yuki, Michiko, Emoto, Yuko, Yoshizawa, Katsuhiko, Yuri, Takashi, Tsubura, Airo
Format: Article
Language:English
Subjects:
Bacteria
Biopsy
Immunohistochemistry
Intestinal infection
Single Case
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Summary:Intestinal spirochetosis (IS) in humans is characterized by spirochetal microorganisms attached to the luminal surface of the colonic epithelium. In the present case, attached organisms appeared as 3- to 4 μm-thick (average thickness, 3.4 μm) basophilic fringes or haze in HE-stained endoscopic biopsy specimens. The basophilic fringes were clearly labeled by Treponema pallidum antiserum. Because IS is relatively rare in developed countries, thin basophilic fringes characteristic of IS are readily overlooked. Thus, the recognition of histological characteristics of this disease is important for its diagnosis.
ISSN:1662-0631
1662-0631
DOI:10.1159/000452212