Can osteoporosis increase the incidence of heart failure in adults?

Background: Recent studies have suggested shared comorbidities between heart failure and osteoporosis. In addition, patients with osteoporosis are associated with increased risks of developing cardiovascular disease. Methods: A retrospective cohort analysis was conducted to determine the association...

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Bibliographic Details
Published in:Current medical research and opinion 2017-06, Vol.33 (6), p.1119-1125
Main Authors: Chiu, Chiung-Zuan, Yeh, Jiann-Horng, Shyu, Kou-Gi, Hou, Sheng-Mou, Lin, Cheng-Li, Liang, Ji-An
Format: Article
Language:English
Subjects:
Aged
Cohort Studies
Comorbidity
Databases, Factual
Female
heart failure
Heart Failure - epidemiology
Heart Failure - etiology
Humans
Incidence
Male
Middle Aged
osteoporosis
Osteoporosis - complications
Osteoporosis - epidemiology
Proportional Hazards Models
retrospective cohort analysis
Retrospective Studies
Risk Factors
Taiwan
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Summary:Background: Recent studies have suggested shared comorbidities between heart failure and osteoporosis. In addition, patients with osteoporosis are associated with increased risks of developing cardiovascular disease. Methods: A retrospective cohort analysis was conducted to determine the association between osteoporosis and heart failure. Data was from the Longitudinal Health Insurance Database 2000 (LHID 2000), Taiwan. Patients with newly diagnosed osteoporosis were identified, and osteoporosis-free controls were randomly selected from the general population and frequency matched according to age, sex, and index year using the LHID 2000. We analyzed the risks of heart failure using Cox proportional-hazards regression models. Results: During the mean follow-up of 7.1 ± 3.5 years, the cumulative incidence of heart failure was 2.24% higher in the osteoporosis cohort than in the comparison cohort (p 
ISSN:0300-7995
1473-4877
DOI:10.1080/03007995.2017.1308343