Salivary microbiota in individuals with different levels of caries experience

This study compared salivary bacterial profiles in two groups having a 10-fold difference in levels of caries experience, as it was hypothesized that the composition of the salivary microbiota might associate with the levels of caries experience. Bacterial profiles in stimulated saliva samples from...

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Bibliographic Details
Published in:Journal of oral microbiology 2017-01, Vol.9 (1), p.1270614-8
Main Authors: Belstrøm, Daniel, Holmstrup, Palle, Fiehn, Nils-Erik, Kirkby, Nikolai, Kokaras, Alexis, Paster, Bruce J., Bardow, Allan
Format: Article
Language:English
Subjects:
Bacteria
Caries susceptibility
clinical studies/trials
Correlation analysis
Data processing
Dental caries
HOMINGS
Longitudinal studies
microbiology
Microbiomes
Microbiota
oral diagnosis
Oral hygiene
Original
Population
Relative abundance
Risk factors
Saliva
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Summary:This study compared salivary bacterial profiles in two groups having a 10-fold difference in levels of caries experience, as it was hypothesized that the composition of the salivary microbiota might associate with the levels of caries experience. Bacterial profiles in stimulated saliva samples from 85 individuals with low levels of caries experience (healthy group) and 79 individuals with high levels of caries experience (caries group) were analyzed by means of the Human Oral Microbiome Identification Next Generation Sequencing (HOMINGS) technique. Subsequently, saliva samples from caries-free individuals in the healthy group (n = 57) and the caries group (n = 31) were compared. A significantly higher α-diversity (p 
ISSN:2000-2297
2000-2297
DOI:10.1080/20002297.2016.1270614