Visceral adipose tissue is more strongly associated with insulin resistance than subcutaneous adipose tissue in Chinese subjects with pre-diabetes

Aims: To investigate the value of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) in a cohort of a community's residents who were diagnosed as pre-diabetes, and to evaluate the association of VAT and SAT with insulin resistance. Methods: This study was based on cross-section...

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Bibliographic Details
Published in:Current medical research and opinion 2018-01, Vol.34 (1), p.123-129
Main Authors: Liu, Lin, Feng, Jitao, Zhang, Gong, Yuan, Xiaodan, Li, Fan, Yang, Tingting, Hao, Shujie, Huang, Dejian, Hsue, Cunyi, Lou, Qinging
Format: Article
Language:English
Subjects:
insulin resistance
Pre-diabetes
subcutaneous adipose tissue
visceral adipose tissue
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Summary:Aims: To investigate the value of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) in a cohort of a community's residents who were diagnosed as pre-diabetes, and to evaluate the association of VAT and SAT with insulin resistance. Methods: This study was based on cross-sectional analysis of data from 107 adults. VAT and SAT were assessed by computed tomography. Insulin resistance was defined by homeostasis model assessment of insulin resistance >2.69. The relationship of VAT and SAT with insulin resistance were examined by linear regression. Logistic regression was used to analyze the association of VAT and SAT with insulin resistance. Results: A total of 87 subjects had VAT ≥100 cm 2 . Thirty-six out of 107 (33.6%) subjects were detected to have insulin resistance, 71 were normal (66.4%), and all had insulin resistance with VAT ≥100 cm 2 . VAT (r = 0.378, p 
ISSN:0300-7995
1473-4877
DOI:10.1080/03007995.2017.1364226