Mid wall fibrosis on CMR with late gadolinium enhancement may predict prognosis for LVAD and transplantation risk in patients with newly diagnosed dilated cardiomyopathy-preliminary observations from a high-volume transplant centre

Patients with newly diagnosed dilated cardiomyopathy (DCM) and advanced heart failure have a very high morbidity and mortality with an unpredictable clinical course. We investigated the role of cardiovascular magnetic resonance (CMR) imaging using late gadolinium enhancement (LGE) in this cohort of...

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Bibliographic Details
Published in:ESC Heart Failure 2015-12, Vol.2 (4), p.150
Main Authors: Venero, Jose V, Doyle, Mark, Shah, Moneal, Rathi, Vikas K, Yamrozik, June A, Williams, Ronald B, Vido, Diane A, Rayarao, Geetha, Benza, Raymond, Murali, Srinivas, Glass, Jerry, Olson, Peter, Sokos, George, Biederman, Robert W W
Format: Article
Language:English
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Summary:Patients with newly diagnosed dilated cardiomyopathy (DCM) and advanced heart failure have a very high morbidity and mortality with an unpredictable clinical course. We investigated the role of cardiovascular magnetic resonance (CMR) imaging using late gadolinium enhancement (LGE) in this cohort of high-risk patients. We hypothesized that LGE has high prognostic value in primary DCM patients referred for possible transplantation/left ventricular assist device (LVAD) consideration. Over 49 consecutive months, 61 consecutives DCM patients were referred for standard CMR(1.5T, GE) to interrogate the LV pattern, distribution, and extent of LGE (MultiHance, Princeton, NJ). Inclusion criteria for a primary non-ischaemic DCM and EF
ISSN:2055-5822
DOI:10.1002/ehf2.12041