α-TCP cements prepared by syringe-foaming: Influence of Na 2 HPO 4 and surfactant concentration

The lack of intrinsic open porosity in calcium phosphate cements slows down the resorption rate and bone ingrowth when implanted In Vivo. In this study, macroporous structures were obtained by mixing α-TCP cement with a foamed liquid phase containing different concentrations of sodium hydrogen phosp...

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Bibliographic Details
Published in:Materials science & engineering. C, Materials for biological applications Materials for biological applications, 2017-12, Vol.81, p.148
Main Authors: Vásquez, A F, Domínguez, S, Loureiro Dos Santos, L A
Format: Article
Language:English
Subjects:
Bone Cements
Calcium Phosphates
Materials Testing
Phosphates
Porosity
Powders
Surface-Active Agents - chemistry
Syringes
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Summary:The lack of intrinsic open porosity in calcium phosphate cements slows down the resorption rate and bone ingrowth when implanted In Vivo. In this study, macroporous structures were obtained by mixing α-TCP cement with a foamed liquid phase containing different concentrations of sodium hydrogen phosphate and a nonionic surfactant. The cement paste was prepared by hand mixing in a novel system of two syringes connected by a tube. Two different liquid to powder (L/P) ratios were used to prepare the cement paste. The cement samples showed open macropores with diameters>100μm. The specimens prepared with lower L/P ratio showed smaller porosity, macroporosity and pore size distribution. The cohesion of the cement paste in liquid solutions was assessed by adding 2wt% sodium alginate to the liquid phase. This study suggests that the final macrostructure of the foamed cements can be controlled by varying the phosphate and surfactant concentrations in the liquid phase and the L/P ratio.
ISSN:1873-0191