Mental disorders and drug/alcohol use in patients commencing extensively drug-resistant tuberculosis treatment

Mental disorders and alcohol/drug use worsen treatment outcomes for multidrug-resistant tuberculosis (TB), but data are lacking for extensively drug-resistant (XDR) TB. We investigated the association of baseline mental disorders and alcohol/drug use on XDR-TB treatment outcomes in a retrospective s...

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Bibliographic Details
Published in:Public health action 2017-09, Vol.7 (3), p.237-239
Main Authors: Scuffell, J., Boccia, D., Velarde, F. Garcia, Leon, S. R., Raviola, G., Lecca, L., Galea, J. T.
Format: Article
Language:English
Subjects:
Alcohol
Anxiety
Depression
Psychosis
Short Communication
Xdr-Tb
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Summary:Mental disorders and alcohol/drug use worsen treatment outcomes for multidrug-resistant tuberculosis (TB), but data are lacking for extensively drug-resistant (XDR) TB. We investigated the association of baseline mental disorders and alcohol/drug use on XDR-TB treatment outcomes in a retrospective study of 53 XDR-TB Peruvian patients during 2010-2012. Logistic regression estimated the odds ratios for unfavourable XDR-TB treatment outcomes. Overall treatment success was 25%. Mental disorders and drug/alcohol use were found in respectively 22.4% and 20.4% of patients; neither were associated with unfavourable treatment outcomes. Future research should explore the relationship between mental health and drug/alcohol use in XDR-TB treatment outcomes.
ISSN:2220-8372
2220-8372
DOI:10.5588/pha.17.0044