Schizencephaly and Porencephaly Due to Fetal Intracranial Hemorrhage : A Report of Two Cases

[ABSTRACT] Schizencephaly and porencephaly are extremely rare types of cortical dysplasia. Case 1: Prenatal magnetic resonance imaging (MRI) showed wide clefts in the frontal and parietal lobes bilaterally. On postnatal day 3, MRI T2-weighted images showed multiple hypointensities in the clefts and...

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Bibliographic Details
Published in:YONAGO ACTA MEDICA 2017, Vol.60 (4), p.241-245
Main Authors: Harada, Takashi, Uegaki, Takashi, Arata, Kazuya, Tsunetou, Takako, Taniguchi, Fuminori, Harada, Tasuku
Format: Article
Language:English
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Summary:[ABSTRACT] Schizencephaly and porencephaly are extremely rare types of cortical dysplasia. Case 1: Prenatal magnetic resonance imaging (MRI) showed wide clefts in the frontal and parietal lobes bilaterally. On postnatal day 3, MRI T2-weighted images showed multiple hypointensities in the clefts and ventricular walls, suggestive of hemosiderosis secondary to intracranial hemorrhage. Case 2: Prenatal MRI showed bilateral cleft and cyst formation in the fetal cerebrum, as well as calcification and hemosiderosis indicative of past hemorrhage. T2-weighted images showed hypointensities in the same regions as the calcification, corresponding with hemosiderosis due to intracranial hemorrhage on postnatal day 10. Thus, prenatal MRI was useful for diagnosing schizencephaly and porencephaly. Schizencephaly and porencephaly were thought to be due to fetal intracranial hemorrhage, which, in the porencephaly case, may have been related to a mutation of COL4A1.
ISSN:0513-5710
DOI:10.33160/yam.2017.12.005