Immunodominance hierarchy of influenza subtype-specific neutralizing antibody response as a hurdle to effectiveness of polyvalent vaccine

Strengthening of immunodominance hierarchy of influenza subtype-specific neutralizing antibody response by annual polyvalent vaccinations could increase the variation of vaccine effectiveness by subtype. Therefore, we suggest the assessment of neutralizing antibody titer prior to seasonal vaccinatio...

Full description

Saved in:
Bibliographic Details
Published in:Human vaccines & immunotherapeutics 2018-10, Vol.14 (10), p.2537-2539
Main Authors: Lee, Hoyoung, Shim, Eun Hyoung, You, Sooseong
Format: Article
Language:English
Subjects:
immunodominance hierarchy
Influenza
vaccine effectiveness
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Strengthening of immunodominance hierarchy of influenza subtype-specific neutralizing antibody response by annual polyvalent vaccinations could increase the variation of vaccine effectiveness by subtype. Therefore, we suggest the assessment of neutralizing antibody titer prior to seasonal vaccination and recommend the inoculation of only strains lower than protective levels.
ISSN:2164-5515
2164-554X
DOI:10.1080/21645515.2018.1482172