Molecular epidemiology of carbapenem-resistant isolates of Acinetobacter baumannii in Argentina

• Published in: Revista argentina de microbiología 2019-07, Vol.51 (3), p.247
• Main Authors: H Rodríguez, Carlos, Nastro, Marcela, A Flores, Silvia, Rodriguez, Mónica, Spinozzi, Mariela, Bruni, Geni, L López, Ana, David, Viviana, S Aiassa, Maria, A Marqués, Isabel, R Navarro, Osvaldo, Paniccia, Laura, Famiglietti, Angela
• Format: Article
• Language: eng ; spa
• Subjects: Acinetobacter baumannii - drug effects; Acinetobacter baumannii - enzymology; Acinetobacter baumannii - genetics; Acinetobacter baumannii - isolation & purification; Acinetobacter Infections - epidemiology; Acinetobacter Infections - microbiology; Argentina - epidemiology; Bacterial Proteins - genetics; beta-Lactam Resistance; beta-Lactamases - genetics; Carbapenems - pharmacology; Cross Infection - epidemiology; Cross Infection - microbiology; Humans
• ISSN: 0325-7541
• DOI: 10.1016/j.ram.2017.12.004

One hundred sequential, epidemiologically unrelated carbapenem-resistant- Acinetobacter baumannii isolates from 11 hospitals in 10 Argentine provinces were collected between January and August 2016. Genes coding for Ambler class D and B carbapenemases were investigated by PCR using specific primers. All isolates were typed using the 3-locus sequence typing and bla like sequence-based typing techniques. The bla gene was recovered in all isolates studied. The population of carbapenem-resistant- A. baumannii in Argentina was principally associated with ST1 (45%), ST25 (34%) and ST79 (15%). ST25 was recovered in all the regions studied and CC2 was not detected.