Standardization of the HbA 2 Assay

A project for the standardization of HbA was launched by the IFCC back in 2004. In this work we report on the state-of-the-art of the project on standardization of HbA . Data obtained from various EQAS studies, and from previous experimental evaluations, are presented. We have proven that biases bet...

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Bibliographic Details
Published in:EJIFCC 2018-12, Vol.29 (4), p.298
Main Authors: Paleari, Renata, Mosca, Andrea
Format: Article
Language:English
Online Access:Get full text
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Summary:A project for the standardization of HbA was launched by the IFCC back in 2004. In this work we report on the state-of-the-art of the project on standardization of HbA . Data obtained from various EQAS studies, and from previous experimental evaluations, are presented. We have proven that biases between various commercial methods are still currently significant. We have also shown that calibration by commutable control materials may halve the inter-method variability. The foundation of the reference system for HbA , together with a brief preliminary presentation of the proposed primary reference measurement procedure based on ID-MS are outlined.
ISSN:1650-3414
1650-3414