Eye-Sparing Treatment for Diffuse Invasive Conjunctival Melanoma

The management of patients with diffuse invasive conjunctival melanoma focuses on local tumor control and screening for metastasis. Despite the lack of consensus on the benefit of sentinel lymph node biopsy for these neoplasms, the information obtained by histopathology is useful for tumor staging a...

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Bibliographic Details
Published in:Ocular oncology and pathology 2018-06, Vol.4 (4), p.261-266
Main Authors: Chaves, Leandro J., Huth, Bradley, Augsburger, James J., Correa, Zelia M.
Format: Article
Language:English
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Novel Insights from Clinical Practice
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Summary:The management of patients with diffuse invasive conjunctival melanoma focuses on local tumor control and screening for metastasis. Despite the lack of consensus on the benefit of sentinel lymph node biopsy for these neoplasms, the information obtained by histopathology is useful for tumor staging and treatment planning. Due to the lack of evidence of survival improvement, orbital exenteration is being performed with diminishing frequency. We describe a patient with diffuse invasive conjunctival melanoma and lymph node involvement treated by tumor debulking, brachytherapy (custom unshielded radioactive device), and adjuvant ipilimumab who has had a favorable outcome without emergence of local tumor relapse or distant metastasis during 16 months of follow up.
ISSN:2296-4681
2296-4657
DOI:10.1159/000485978