New Generation Fish Oil And Olive Oil Lipid On Prevention Of Oxidative Damage In Preterm Infants

Parenteral nutrition (PN) has been widely used in preterm infants. Lipid solutions used for PN were reported to be associated with oxidative stress and related morbidities. The aim of this study was to compare the effectiveness of new generation lipid emulsion (SMOFLipid) and olive-oil based lipid e...

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Bibliographic Details
Published in:Pediatrics international 2019-02
Main Authors: Ozkan, Hilal, Köksal, Nilgün, Dorum, Bayram Ali, Kocael, Fatma, Ozarda, Yesim, Doğan, Pelin, Guney Varal, Ipek, Bagci, Onur
Format: Article
Language:English
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Summary:Parenteral nutrition (PN) has been widely used in preterm infants. Lipid solutions used for PN were reported to be associated with oxidative stress and related morbidities. The aim of this study was to compare the effectiveness of new generation lipid emulsion (SMOFLipid) and olive-oil based lipid emulsion for prevention of PN associated oxidative damage. Preterm infants 0.05), and the rate of severe BPD was significantly lower in the SMOFlipid group. To our best of knowledge, this is the first study which suggested that SMOFlipid might decrease oxidative damage and oxidative-stress associated morbidities compared with olive oil based emulsion in preterm infants. This article is protected by copyright. All rights reserved.
ISSN:1442-200X