Vitamin B 12 Status in Pregnant Adolescents and Their Infants

Vitamin B deficiency has been associated with increased risk of adverse pregnancy outcomes. Few prospective studies have investigated the burden or determinants of vitamin B deficiency early in life, particularly among pregnant adolescents and their children. The objectives of this study were to det...

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Bibliographic Details
Published in:Nutrients 2019-02, Vol.11 (2)
Main Authors: Finkelstein, Julia L, Guillet, Ronnie, Pressman, Eva K, Fothergill, Amy, Guetterman, Heather M, Kent, Tera R, O'Brien, Kimberly O
Format: Article
Language:English
Subjects:
Biomarkers - blood
Female
Gestational Age
Humans
Infant, Newborn
Male
Pregnancy
Pregnancy Outcome
Vitamin B 12 - blood
Vitamin B 12 Deficiency - blood
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Summary:Vitamin B deficiency has been associated with increased risk of adverse pregnancy outcomes. Few prospective studies have investigated the burden or determinants of vitamin B deficiency early in life, particularly among pregnant adolescents and their children. The objectives of this study were to determine the prevalence of vitamin B deficiency and to examine associations between maternal and neonatal vitamin B status in a cohort study of healthy pregnant adolescents. Serum vitamin B and folate concentrations were measured in adolescents at mid-gestation ( = 124; 26.4 ± 3.5 weeks) and delivery ( = 131; 40.0 ± 1.3 weeks), and in neonates at birth using cord blood. Linear regression was used to examine associations between maternal and neonatal vitamin B status. Although the prevalence of vitamin B deficiency (
ISSN:2072-6643
DOI:10.3390/nu11020397