Spirometric Findings in Capacitor Workers Occupationally Exposed to Polychlorinated Biphenyls (PCBs)

Spirometric findings (forced vital capacity [FVC], forced expiratory volume at one second [FEV₁J, FEV₁/FVC) in a population of capacitor workers with occupational exposure to polychlorinated biphenyls (PCBs) are described during active PCB use (1976) and following the PCB ban (1979 and 1983). The in...

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Bibliographic Details
Published in:Journal of occupational and environmental medicine 1986-06, Vol.28 (6), p.453-456
Main Authors: Lawton, Richard W., Ross, Marie R., Feingold, Joseph
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Body Weight
Chemical and industrial products toxicology. Toxic occupational diseases
Female
Forced Expiratory Volume
Humans
Longitudinal Studies
Male
Medical sciences
Middle Aged
New York
Occupational Diseases - chemically induced
Occupational Diseases - physiopathology
ORIGINAL ARTICLES
Polychlorinated Biphenyls - adverse effects
Smoking
Spirometry
Statistics as Topic
Toxicology
Various organic compounds
Vital Capacity
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Description
Summary:Spirometric findings (forced vital capacity [FVC], forced expiratory volume at one second [FEV₁J, FEV₁/FVC) in a population of capacitor workers with occupational exposure to polychlorinated biphenyls (PCBs) are described during active PCB use (1976) and following the PCB ban (1979 and 1983). The initial finding of restrictive impairment (16%) in 1976 was not supported by chest roentgenogram findings, nor confirmed in 1979 and 1983, and was interpreted as artifactual due to test operator inexperience and inadequate expiratory efforts. Obstructive impairment was consistently found in 15% of the total population in 1976 and 1979. A history of respiratory illness and/or symptomatology and reduced FEV₁/FVC was correlated with PCB exposure and serum PCB levels (lower homologs) in females in 1976, but not in males. Smoking was correlated with reduced FEVX values. No correlation of spirometric variables with past exposure or serum PCB levels was found for either sex in 1979.
ISSN:0096-1736
1076-2752
2332-3795
DOI:10.1097/00043764-198606000-00014