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Quantification of the β 2 -Adrenergic Feed Additives Ractopamine and Salbutamol by Reductive Amination-Assisted Modification

A reductive amination-assisted method was used to synthesize standards and internal standards of ractopamine and salbutamol. Standard and internal standard analogs were fabricated by isotopic formaldehydes and sodium cyanoborohydride. A quantitative method of modified ractopamine and salbutamol was...

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Bibliographic Details
Published in:Journal of food protection 2019-04, Vol.82 (4), p.696
Main Authors: Shen, Po-Tsun, Wu, You-Ying, Chang, Yu-Tzu, Cheng, Chieh-Wen, Huang, Mei-Fang, Chen, Ziyu, Shiue, Yow-Ling, Liang, Shih-Shin
Format: Article
Language:English
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Summary:A reductive amination-assisted method was used to synthesize standards and internal standards of ractopamine and salbutamol. Standard and internal standard analogs were fabricated by isotopic formaldehydes and sodium cyanoborohydride. A quantitative method of modified ractopamine and salbutamol was successfully validated. The reductive amination-assisted method enhances the signal for MS detection.
ISSN:1944-9097