3D hierarchical hollow hydrangea-like Fe 3+ @ɛ-MnO 2 microspheres with excellent electrochemical performance for dopamine and hydrogen peroxide

• Published in: Biosensors & bioelectronics 2019-03, Vol.133, p.250
• Main Authors: Song, Haiyan, Zhao, Hui, Zhang, Xianfa, Xu, Yingming, Cheng, Xiaoli, Gao, Shan, Huo, Lihua
• Format: Article
• Language: English
• ISSN: 1873-4235
• DOI: 10.1016/j.bios.2019.03.017

Construction a sensor to accurately detect dopamine (DA) and hydrogen peroxide (H O ) is meaningful due to their close relation to the health of organisms. In this work, one-step hydrothermal method was employed to synthesize hierarchical hollow hydrangea-like Fe @ɛ-MnO microspheres constructed by interconnected nanosheets, and the growth mechanism of the microspheres (n /n = 0.6) was also investigated in detail. The material was used to construct an electrochemical sensor for DA and H O detection with the linear range of 0.02-78 μmoL and 0.000133-5.19 mmoL , respectively. The detection limit and sensitivity for DA and H O are 5 and 50 nmoL (S/N = 3), 7034.1 and 242.6 µA m(mol·L ) cm , respectively. Furthermore, the sensor was successfully applied to the detection of DA and H O in serum and urine samples, indicating a potential value of this work in the pharmaceutical and environmental fields.