Prostaglandins and cesarean delivery for nonreassuring fetal status in patients delivering small-for-gestational age neonates at term

Objective: Growth-restricted fetuses have been excluded from many randomized trials of prostaglandins for labor induction. As prostaglandins, particularly misoprostol, are associated with increased rates of cesarean delivery for nonreassuring fetal heart tracing, it is important to assess their safe...

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Bibliographic Details
Published in:The journal of maternal-fetal & neonatal medicine 2021-02, Vol.34 (3), p.366-372
Main Authors: Rosenbloom, Joshua I., Rhoades, Janine S., Woolfolk, Candice L., Stout, Molly J., Tuuli, Methodius G., Macones, George A., Cahill, Alison G.
Format: Article
Language:English
Subjects:
Cesarean delivery
Female
Fetal Distress
Gestational Age
Humans
induction of labor
Infant
Infant, Newborn
Labor, Induced - adverse effects
Labor, Obstetric
nonreassuring fetal heart tracing
Pregnancy
Prostaglandins
Retrospective Studies
small-for-gestational age
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Summary:Objective: Growth-restricted fetuses have been excluded from many randomized trials of prostaglandins for labor induction. As prostaglandins, particularly misoprostol, are associated with increased rates of cesarean delivery for nonreassuring fetal heart tracing, it is important to assess their safety in pregnancies at higher risk of this complication. The objective of this study was to estimate the association between use of prostaglandins for labor induction in term singleton pregnancies complicated by delivery of small-for-gestational age (SGA) neonates and the risk of cesarean delivery for nonreassuring fetal status (NRFS). Materials and methods: Retrospective cohort study of singleton deliveries ≥37 weeks following induction of labor in patients with SGA (birthweight
ISSN:1476-7058
1476-4954
DOI:10.1080/14767058.2019.1608177