New Sensor and Wearable Technologies to Aid in the Diagnosis and Treatment Monitoring of Parkinson's Disease

Parkinson's disease (PD) is a degenerative disorder of the brain characterized by the impairment of the nigrostriatal system. This impairment leads to specific motor manifestations (i.e., bradykinesia, tremor, and rigidity) that are assessed through clinical examination, scales, and patient-rep...

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Bibliographic Details
Published in:Annual review of biomedical engineering 2019-06, Vol.21 (1), p.111-143
Main Authors: Monje, Mariana H.G, Foffani, Guglielmo, Obeso, José, Sánchez-Ferro, Álvaro
Format: Article
Language:English
Subjects:
biomedical
movement disorders
Parkinson's disease
remote sensing technology
technological innovations
technology assessment
wearable electronic devices
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Summary:Parkinson's disease (PD) is a degenerative disorder of the brain characterized by the impairment of the nigrostriatal system. This impairment leads to specific motor manifestations (i.e., bradykinesia, tremor, and rigidity) that are assessed through clinical examination, scales, and patient-reported outcomes. New sensor-based and wearable technologies are progressively revolutionizing PD care by objectively measuring these manifestations and improving PD diagnosis and treatment monitoring. However, their use is still limited in clinical practice, perhaps because of the absence of external validation and standards for their continuous use at home. In the near future, these systems will progressively complement traditional tools and revolutionize the way we diagnose and monitor patients with PD.
ISSN:1523-9829
1545-4274
DOI:10.1146/annurev-bioeng-062117-121036