Stercufoetin A, new oleanane-type triterpenoid from the leaves of Sterculia foetida L

From the leaves of Sterculia foetida L., one new oleanane-type triterpenoid, named stercufoetin A (1) together with four known ones, vergatic acid (2), β-amyrin (3), oleanolic acid (4) and maslinic acid (5) were purified by diversely chromatographic methods. Their structures were proposed by HR-APCI...

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Bibliographic Details
Published in:Natural product research 2021-04, Vol.35 (7), p.1226-1231
Main Authors: Pham, Nguyen Kim Tuyen, Nguyen, Trung Duan, Doan, Tran Duy Cuong, Ha, Tuan Dat, Tran, Nguyen Minh An, Tran, Trong Duc, Mai, Dinh Tri, Nguyen, Tan Phat
Format: Article
Language:English
Subjects:
Carbon-13 Magnetic Resonance Spectroscopy
Cell Death - drug effects
Cell Line, Tumor
Chromatography
Cytotoxicity
Humans
NMR
Nuclear magnetic resonance
Oleanolic acid
Oleanolic Acid - analogs & derivatives
Oleanolic Acid - chemistry
Oleanolic Acid - isolation & purification
Oleanolic Acid - pharmacology
Plant Extracts - chemistry
Plant Leaves - chemistry
Proton Magnetic Resonance Spectroscopy
stercufoetin A
Sterculia - chemistry
Sterculia foetida
Sterculiaceae
Triterpenes - chemistry
Triterpenes - isolation & purification
Triterpenes - pharmacology
triterpenoid
Tumor cell lines
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Summary:From the leaves of Sterculia foetida L., one new oleanane-type triterpenoid, named stercufoetin A (1) together with four known ones, vergatic acid (2), β-amyrin (3), oleanolic acid (4) and maslinic acid (5) were purified by diversely chromatographic methods. Their structures were proposed by HR-APCI-MS and NMR experiments. Compounds (2-5) were notified for the first time from this species. Compound 1 showed weak cytotoxic effect against three human cancer cell lines (MCF-7, HepG2 and HeLa) using SRB assay.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2019.1644508