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Stercufoetin A, new oleanane-type triterpenoid from the leaves of Sterculia foetida L
From the leaves of Sterculia foetida L., one new oleanane-type triterpenoid, named stercufoetin A (1) together with four known ones, vergatic acid (2), β-amyrin (3), oleanolic acid (4) and maslinic acid (5) were purified by diversely chromatographic methods. Their structures were proposed by HR-APCI...
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Published in: | Natural product research 2021-04, Vol.35 (7), p.1226-1231 |
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container_title | Natural product research |
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creator | Pham, Nguyen Kim Tuyen Nguyen, Trung Duan Doan, Tran Duy Cuong Ha, Tuan Dat Tran, Nguyen Minh An Tran, Trong Duc Mai, Dinh Tri Nguyen, Tan Phat |
description | From the leaves of Sterculia foetida L., one new oleanane-type triterpenoid, named stercufoetin A (1) together with four known ones, vergatic acid (2), β-amyrin (3), oleanolic acid (4) and maslinic acid (5) were purified by diversely chromatographic methods. Their structures were proposed by HR-APCI-MS and NMR experiments. Compounds (2-5) were notified for the first time from this species. Compound 1 showed weak cytotoxic effect against three human cancer cell lines (MCF-7, HepG2 and HeLa) using SRB assay. |
doi_str_mv | 10.1080/14786419.2019.1644508 |
format | article |
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subjects | Carbon-13 Magnetic Resonance Spectroscopy Cell Death - drug effects Cell Line, Tumor Chromatography Cytotoxicity Humans NMR Nuclear magnetic resonance Oleanolic acid Oleanolic Acid - analogs & derivatives Oleanolic Acid - chemistry Oleanolic Acid - isolation & purification Oleanolic Acid - pharmacology Plant Extracts - chemistry Plant Leaves - chemistry Proton Magnetic Resonance Spectroscopy stercufoetin A Sterculia - chemistry Sterculia foetida Sterculiaceae Triterpenes - chemistry Triterpenes - isolation & purification Triterpenes - pharmacology triterpenoid Tumor cell lines |
title | Stercufoetin A, new oleanane-type triterpenoid from the leaves of Sterculia foetida L |
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