Forensic effectiveness and genetic distribution of 23 autosomal STRs included in Verifiler Plus TM multiplex in a population sample from Madhya Pradesh, India

We report here the first ever global study on genetic polymorphism using a Verifiler Plus autosomal STR multiplex system. The study evaluated genetic characteristics of 23 autosomal STRs in 200 unrelated residents of Guna district of Madhya Pradesh, India. Allele frequencies and forensic parameters...

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Bibliographic Details
Published in:International journal of legal medicine 2020-07, Vol.134 (4), p.1327
Main Authors: Shrivastava, Pankaj, Kaitholia, Kamlesh, Kumawat, R K, Dixit, Shivani, Dash, Hirak Ranjan, Srivastava, Ankit, Baroniya, Yash, Mishra, Aditi, Kushwaha, Pushpesh, Rana, Manisha, Dixit, Akansha, Sarawagi, Tanya, Bhatt, Alay, Sharma, Harsh, Sinha, Moumita, Chaubey, Gyaneshwer
Format: Article
Language:English
Subjects:
DNA Fingerprinting - instrumentation
DNA Fingerprinting - methods
Ethnic Groups - genetics
Forensic Genetics - methods
Gene Frequency
Genetic Markers
Genetics, Population
Humans
India - ethnology
Male
Microsatellite Repeats
Polymorphism, Genetic
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Summary:We report here the first ever global study on genetic polymorphism using a Verifiler Plus autosomal STR multiplex system. The study evaluated genetic characteristics of 23 autosomal STRs in 200 unrelated residents of Guna district of Madhya Pradesh, India. Allele frequencies and forensic parameters are reported. Population comparison analysis was also performed using NJ tree and PCA plot. Penta E marker showed highest power of discrimination (0.938) among all 23 studied markers. The study also presents the first ever global forensic assessment in Indian population on D6S1043 marker (PD 0.937). The results demonstrated that all the 23 markers were highly polymorphic and the Verifiler Plus kit is suitable for forensic purposes in Indian population.
ISSN:1437-1596