Impact of smoking on cardiovascular outcomes in patients with stable coronary artery disease

Smoking is a major preventable risk factor for cardiovascular disease and mortality. However, the 'smoker's paradox' suggests that it is associated with better survival after acute myocardial infarction. We aimed to investigate the impact of smoking on mortality and cardiovascular out...

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Bibliographic Details
Published in:European journal of preventive cardiology 2020-04, p.2047487320918728
Main Authors: Bouabdallaoui, Nadia, Messas, Nathan, Greenlaw, Nicola, Ferrari, Roberto, Ford, Ian, Fox, Kim M, Tendera, Michal, P Naidoo, Datshana, Hassager, Christian, Gabriel Steg, P, Tardif, Jean-Claude
Format: Article
Language:English
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Summary:Smoking is a major preventable risk factor for cardiovascular disease and mortality. However, the 'smoker's paradox' suggests that it is associated with better survival after acute myocardial infarction. We aimed to investigate the impact of smoking on mortality and cardiovascular outcomes in patients with stable coronary artery disease. The international CLARIFY registry included 32,703 patients with stable coronary artery disease between 2009 and 2010. Among the 32,378 patients included in the present analysis, Cox proportional hazards models (adjusted for age, sex, geographic region, prior myocardial infarction, and revascularization status) were used to estimate associations between smoking status and outcomes. Patients were stratified as follows: 41.3% of patients never smoked, 12.5% were current smokers and 46.2% were former smokers. Current smokers were younger than never-smokers and former smokers (59 . 66 and 64 years old, respectively,  
ISSN:2047-4881