Loading…
Improvement in cognitive decline after indirect bypass surgery in adult moyamoya disease: implication of 15 O-gas positron emission tomography
To investigate the characteristics of patients with moyamoya disease (MMD) who show improvement in their cognitive decline after bypass surgery by analyzing the hemodynamic and metabolic parameters of O-gas positron emission tomography (PET). We retrospectively analyzed adult patients with MMD who w...
Saved in:
| Published in: | Annals of nuclear medicine 2020-07, Vol.34 (7), p.467 |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | |
|---|---|
| cites | |
| container_end_page | |
| container_issue | 7 |
| container_start_page | 467 |
| container_title | Annals of nuclear medicine |
| container_volume | 34 |
| creator | Hara, Shoko Kudo, Takumi Hayashi, Shihori Inaji, Motoki Tanaka, Yoji Maehara, Taketoshi Ishii, Kenji Nariai, Tadashi |
| description | To investigate the characteristics of patients with moyamoya disease (MMD) who show improvement in their cognitive decline after bypass surgery by analyzing the hemodynamic and metabolic parameters of
O-gas positron emission tomography (PET).
We retrospectively analyzed adult patients with MMD who were evaluated with PET and cognitive tests before and approximately one year after indirect bypass surgery. The PET parameters of the left Rolandic area were compared between patients who did and did not show improvement in their cognitive decline.
Of the 19 patients analyzed, fourteen (74%) showed improvement in either the verbal or performance intelligence quotient (VIQ or PIQ). Three out of four patients with perioperative infarction experienced significant cognitive decline. The preoperative oxygen extraction fraction (OEF) was significantly higher in patients who showed improvement in their cognitive decline in terms of the PIQ than in those patients who did not (P = 0.03). The postoperative increase in the cerebral metabolic rate of oxygen (CMRO
) was significantly higher in patients who showed improvement in their cognitive decline in terms of the VIQ than in those who did not (P = 0.02).
Adult patients with MMD might show improvement in their cognitive decline after successful indirect bypass surgery if they have a severely increased regional OEF before the surgery and an increased regional CMRO
after the surgery.
URL: https://www.umin.ac.jp/ctr/. Unique identifier: UMIN000027949. |
| format | article |
| fullrecord | <record><control><sourceid>pubmed</sourceid><recordid>TN_cdi_pubmed_primary_32378149</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>32378149</sourcerecordid><originalsourceid>FETCH-pubmed_primary_323781493</originalsourceid><addsrcrecordid>eNqFj81KxEAQhAdB3HX1FaRfILDJZNfoVRQ9efG-9GY6sSXzQ_dkYV7CZ3YDevZQFNRXdagLs667fVvtW2tX5lr1a7ttul3XXJmVbex9V7cPa_P95pPEE3kKGThAH8fAmU8EjvqJAwEOmeSMHAv1GY4loSroLCNJWSbo5imDjwUXgWMlVHoE9mniHjPHAHGAegfv1YgKKSpnOYfkWXWhOfo4CqbPcmMuB5yUbn99Y-5enj-eXqs0Hz25QxL2KOXwd8D-W_gBek9UWA</addsrcrecordid><sourcetype>Index Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Improvement in cognitive decline after indirect bypass surgery in adult moyamoya disease: implication of 15 O-gas positron emission tomography</title><source>Springer Link</source><creator>Hara, Shoko ; Kudo, Takumi ; Hayashi, Shihori ; Inaji, Motoki ; Tanaka, Yoji ; Maehara, Taketoshi ; Ishii, Kenji ; Nariai, Tadashi</creator><creatorcontrib>Hara, Shoko ; Kudo, Takumi ; Hayashi, Shihori ; Inaji, Motoki ; Tanaka, Yoji ; Maehara, Taketoshi ; Ishii, Kenji ; Nariai, Tadashi</creatorcontrib><description>To investigate the characteristics of patients with moyamoya disease (MMD) who show improvement in their cognitive decline after bypass surgery by analyzing the hemodynamic and metabolic parameters of
O-gas positron emission tomography (PET).
We retrospectively analyzed adult patients with MMD who were evaluated with PET and cognitive tests before and approximately one year after indirect bypass surgery. The PET parameters of the left Rolandic area were compared between patients who did and did not show improvement in their cognitive decline.
Of the 19 patients analyzed, fourteen (74%) showed improvement in either the verbal or performance intelligence quotient (VIQ or PIQ). Three out of four patients with perioperative infarction experienced significant cognitive decline. The preoperative oxygen extraction fraction (OEF) was significantly higher in patients who showed improvement in their cognitive decline in terms of the PIQ than in those patients who did not (P = 0.03). The postoperative increase in the cerebral metabolic rate of oxygen (CMRO
) was significantly higher in patients who showed improvement in their cognitive decline in terms of the VIQ than in those who did not (P = 0.02).
Adult patients with MMD might show improvement in their cognitive decline after successful indirect bypass surgery if they have a severely increased regional OEF before the surgery and an increased regional CMRO
after the surgery.
URL: https://www.umin.ac.jp/ctr/. Unique identifier: UMIN000027949.</description><identifier>EISSN: 1864-6433</identifier><identifier>PMID: 32378149</identifier><language>eng</language><publisher>Japan</publisher><subject>Adult ; Cognitive Dysfunction - diagnostic imaging ; Cognitive Dysfunction - physiopathology ; Female ; Hemodynamics ; Humans ; Image Processing, Computer-Assisted ; Male ; Moyamoya Disease - physiopathology ; Moyamoya Disease - surgery ; Oxygen Radioisotopes ; Positron-Emission Tomography ; Retrospective Studies ; Young Adult</subject><ispartof>Annals of nuclear medicine, 2020-07, Vol.34 (7), p.467</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0003-1097-2738</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32378149$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hara, Shoko</creatorcontrib><creatorcontrib>Kudo, Takumi</creatorcontrib><creatorcontrib>Hayashi, Shihori</creatorcontrib><creatorcontrib>Inaji, Motoki</creatorcontrib><creatorcontrib>Tanaka, Yoji</creatorcontrib><creatorcontrib>Maehara, Taketoshi</creatorcontrib><creatorcontrib>Ishii, Kenji</creatorcontrib><creatorcontrib>Nariai, Tadashi</creatorcontrib><title>Improvement in cognitive decline after indirect bypass surgery in adult moyamoya disease: implication of 15 O-gas positron emission tomography</title><title>Annals of nuclear medicine</title><addtitle>Ann Nucl Med</addtitle><description>To investigate the characteristics of patients with moyamoya disease (MMD) who show improvement in their cognitive decline after bypass surgery by analyzing the hemodynamic and metabolic parameters of
O-gas positron emission tomography (PET).
We retrospectively analyzed adult patients with MMD who were evaluated with PET and cognitive tests before and approximately one year after indirect bypass surgery. The PET parameters of the left Rolandic area were compared between patients who did and did not show improvement in their cognitive decline.
Of the 19 patients analyzed, fourteen (74%) showed improvement in either the verbal or performance intelligence quotient (VIQ or PIQ). Three out of four patients with perioperative infarction experienced significant cognitive decline. The preoperative oxygen extraction fraction (OEF) was significantly higher in patients who showed improvement in their cognitive decline in terms of the PIQ than in those patients who did not (P = 0.03). The postoperative increase in the cerebral metabolic rate of oxygen (CMRO
) was significantly higher in patients who showed improvement in their cognitive decline in terms of the VIQ than in those who did not (P = 0.02).
Adult patients with MMD might show improvement in their cognitive decline after successful indirect bypass surgery if they have a severely increased regional OEF before the surgery and an increased regional CMRO
after the surgery.
URL: https://www.umin.ac.jp/ctr/. Unique identifier: UMIN000027949.</description><subject>Adult</subject><subject>Cognitive Dysfunction - diagnostic imaging</subject><subject>Cognitive Dysfunction - physiopathology</subject><subject>Female</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted</subject><subject>Male</subject><subject>Moyamoya Disease - physiopathology</subject><subject>Moyamoya Disease - surgery</subject><subject>Oxygen Radioisotopes</subject><subject>Positron-Emission Tomography</subject><subject>Retrospective Studies</subject><subject>Young Adult</subject><issn>1864-6433</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNqFj81KxEAQhAdB3HX1FaRfILDJZNfoVRQ9efG-9GY6sSXzQ_dkYV7CZ3YDevZQFNRXdagLs667fVvtW2tX5lr1a7ttul3XXJmVbex9V7cPa_P95pPEE3kKGThAH8fAmU8EjvqJAwEOmeSMHAv1GY4loSroLCNJWSbo5imDjwUXgWMlVHoE9mniHjPHAHGAegfv1YgKKSpnOYfkWXWhOfo4CqbPcmMuB5yUbn99Y-5enj-eXqs0Hz25QxL2KOXwd8D-W_gBek9UWA</recordid><startdate>202007</startdate><enddate>202007</enddate><creator>Hara, Shoko</creator><creator>Kudo, Takumi</creator><creator>Hayashi, Shihori</creator><creator>Inaji, Motoki</creator><creator>Tanaka, Yoji</creator><creator>Maehara, Taketoshi</creator><creator>Ishii, Kenji</creator><creator>Nariai, Tadashi</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><orcidid>https://orcid.org/0000-0003-1097-2738</orcidid></search><sort><creationdate>202007</creationdate><title>Improvement in cognitive decline after indirect bypass surgery in adult moyamoya disease: implication of 15 O-gas positron emission tomography</title><author>Hara, Shoko ; Kudo, Takumi ; Hayashi, Shihori ; Inaji, Motoki ; Tanaka, Yoji ; Maehara, Taketoshi ; Ishii, Kenji ; Nariai, Tadashi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_323781493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Cognitive Dysfunction - diagnostic imaging</topic><topic>Cognitive Dysfunction - physiopathology</topic><topic>Female</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted</topic><topic>Male</topic><topic>Moyamoya Disease - physiopathology</topic><topic>Moyamoya Disease - surgery</topic><topic>Oxygen Radioisotopes</topic><topic>Positron-Emission Tomography</topic><topic>Retrospective Studies</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hara, Shoko</creatorcontrib><creatorcontrib>Kudo, Takumi</creatorcontrib><creatorcontrib>Hayashi, Shihori</creatorcontrib><creatorcontrib>Inaji, Motoki</creatorcontrib><creatorcontrib>Tanaka, Yoji</creatorcontrib><creatorcontrib>Maehara, Taketoshi</creatorcontrib><creatorcontrib>Ishii, Kenji</creatorcontrib><creatorcontrib>Nariai, Tadashi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Annals of nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hara, Shoko</au><au>Kudo, Takumi</au><au>Hayashi, Shihori</au><au>Inaji, Motoki</au><au>Tanaka, Yoji</au><au>Maehara, Taketoshi</au><au>Ishii, Kenji</au><au>Nariai, Tadashi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Improvement in cognitive decline after indirect bypass surgery in adult moyamoya disease: implication of 15 O-gas positron emission tomography</atitle><jtitle>Annals of nuclear medicine</jtitle><addtitle>Ann Nucl Med</addtitle><date>2020-07</date><risdate>2020</risdate><volume>34</volume><issue>7</issue><spage>467</spage><pages>467-</pages><eissn>1864-6433</eissn><abstract>To investigate the characteristics of patients with moyamoya disease (MMD) who show improvement in their cognitive decline after bypass surgery by analyzing the hemodynamic and metabolic parameters of
O-gas positron emission tomography (PET).
We retrospectively analyzed adult patients with MMD who were evaluated with PET and cognitive tests before and approximately one year after indirect bypass surgery. The PET parameters of the left Rolandic area were compared between patients who did and did not show improvement in their cognitive decline.
Of the 19 patients analyzed, fourteen (74%) showed improvement in either the verbal or performance intelligence quotient (VIQ or PIQ). Three out of four patients with perioperative infarction experienced significant cognitive decline. The preoperative oxygen extraction fraction (OEF) was significantly higher in patients who showed improvement in their cognitive decline in terms of the PIQ than in those patients who did not (P = 0.03). The postoperative increase in the cerebral metabolic rate of oxygen (CMRO
) was significantly higher in patients who showed improvement in their cognitive decline in terms of the VIQ than in those who did not (P = 0.02).
Adult patients with MMD might show improvement in their cognitive decline after successful indirect bypass surgery if they have a severely increased regional OEF before the surgery and an increased regional CMRO
after the surgery.
URL: https://www.umin.ac.jp/ctr/. Unique identifier: UMIN000027949.</abstract><cop>Japan</cop><pmid>32378149</pmid><orcidid>https://orcid.org/0000-0003-1097-2738</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | EISSN: 1864-6433 |
| ispartof | Annals of nuclear medicine, 2020-07, Vol.34 (7), p.467 |
| issn | 1864-6433 |
| language | eng |
| recordid | cdi_pubmed_primary_32378149 |
| source | Springer Link |
| subjects | Adult Cognitive Dysfunction - diagnostic imaging Cognitive Dysfunction - physiopathology Female Hemodynamics Humans Image Processing, Computer-Assisted Male Moyamoya Disease - physiopathology Moyamoya Disease - surgery Oxygen Radioisotopes Positron-Emission Tomography Retrospective Studies Young Adult |
| title | Improvement in cognitive decline after indirect bypass surgery in adult moyamoya disease: implication of 15 O-gas positron emission tomography |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-30T20%3A42%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Improvement%20in%20cognitive%20decline%20after%20indirect%20bypass%20surgery%20in%20adult%20moyamoya%20disease:%20implication%20of%2015%20O-gas%20positron%20emission%20tomography&rft.jtitle=Annals%20of%20nuclear%20medicine&rft.au=Hara,%20Shoko&rft.date=2020-07&rft.volume=34&rft.issue=7&rft.spage=467&rft.pages=467-&rft.eissn=1864-6433&rft_id=info:doi/&rft_dat=%3Cpubmed%3E32378149%3C/pubmed%3E%3Cgrp_id%3Ecdi_FETCH-pubmed_primary_323781493%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/32378149&rfr_iscdi=true |