Increased IL-8 levels in HIV-infected individuals who initiated ART with CD4 + T cell counts <350 cells/mm 3 - A potential hallmark of chronic inflammation

The identification of inflammatory markers in HIV+ individuals on ART is fundamental since chronic ART-controlled HIV infection is linked to an increased inflammatory state. In this context, we assessed plasma levels of pro-inflammatory cytokines (IL-1β, IL-8, and IL-12p70) of HIV+ individuals who i...

Full description

Saved in:
Bibliographic Details
Published in:Microbes and infection 2020-10, Vol.22 (9), p.474
Main Authors: Ellwanger, Joel Henrique, Valverde-Villegas, Jacqueline María, Kaminski, Valéria de Lima, de Medeiros, Rúbia Marília, Almeida, Sabrina Esteves de Matos, Santos, Breno Riegel, de Melo, Marineide Gonçalves, Hackenhaar, Fernanda Schäfer, Chies, José Artur Bogo
Format: Article
Language:English
Subjects:
Adult
Anti-Retroviral Agents - therapeutic use
Biomarkers - blood
Brazil
Case-Control Studies
CD4 Lymphocyte Count
CD4-Positive T-Lymphocytes
Cytokines - blood
Disease Progression
Female
HIV Infections - blood
HIV Infections - drug therapy
HIV-1
Humans
Inflammation - blood
Inflammation - diagnosis
Interleukin-12
Interleukin-8 - blood
Male
Middle Aged
Viral Load
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The identification of inflammatory markers in HIV+ individuals on ART is fundamental since chronic ART-controlled HIV infection is linked to an increased inflammatory state. In this context, we assessed plasma levels of pro-inflammatory cytokines (IL-1β, IL-8, and IL-12p70) of HIV+ individuals who initiated ART after immunosuppression (CD4 T cell counts
ISSN:1769-714X