The bioavailability of benorylate in hot beverages

It has been recommended that benorylate may be administered with hot beverages to overcome the problem of its relative unpalatability. Urine salicylate recovery used as a measure of bioavailability in 20 normal subjects has shown that hot coffee has no significant effect on drug availability from th...

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Bibliographic Details
Published in:Rheumatology and rehabilitation 1978-02, Vol.17 (1), p.23
Main Authors: Barrett, N A, Pickup, M E, Lowe, J R, Wright, V, Downie, W W
Format: Article
Language:English
Subjects:
Adult
Beverages
Biological Availability
Female
Half-Life
Hot Temperature
Humans
Male
Salicylates - metabolism
Salicylates - urine
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Description
Summary:It has been recommended that benorylate may be administered with hot beverages to overcome the problem of its relative unpalatability. Urine salicylate recovery used as a measure of bioavailability in 20 normal subjects has shown that hot coffee has no significant effect on drug availability from the orally administered suspension.
ISSN:0300-3396
DOI:10.1093/rheumatology/17.1.23