Biochemical analysis between common type and critical type of COVID-19 and clinical value of neutrophil/lymphocyte ratio

To identify the key biochemical indicators that affect the clinical type and outcomes of COVID-19 patients and explore the application of neutrophil/lymphocyte ratio (NLR) in COVID-19. Ninety-three patients with confirmed diagnosis of COVID-19 admitted in Ezhou Central Hospital from February to Apri...

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Bibliographic Details
Published in:Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban 2020-05, Vol.40 (7), p.965
Main Authors: Li, Hongbing, Zhao, Maojun, Xu, Yingsheng
Format: Article
Language:Chinese
Subjects:
Betacoronavirus
Blood Cell Count - standards
Coronavirus Infections - blood
Coronavirus Infections - diagnosis
Coronavirus Infections - physiopathology
COVID-19
Humans
Lymphocytes - cytology
Neutrophils - cytology
Pandemics
Pneumonia, Viral - blood
Pneumonia, Viral - diagnosis
Pneumonia, Viral - physiopathology
Prognosis
Retrospective Studies
ROC Curve
SARS-CoV-2
Severity of Illness Index
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Summary:To identify the key biochemical indicators that affect the clinical type and outcomes of COVID-19 patients and explore the application of neutrophil/lymphocyte ratio (NLR) in COVID-19. Ninety-three patients with confirmed diagnosis of COVID-19 admitted in Ezhou Central Hospital from February to April in 2020 were analyzed. Among them, 43 patients were selected from Intensive Care Unit (ICU) with the diagnosis of critical type of COVID-19, and 50 cases of common type were selected from the Department of Respiratory Medicine. The baseline data, blood routine test and biochemical indexes of the patients were collected on the first day of admission. NLRs of the patients were calculated, and COX survival analysis according to the NLR 4-category method was performed. The patients' outcomes were analyzed with receiver operating curves (ROCs). The patients were divided into two groups according to NLR cutoff value for comparison of the biochemical indexes. Based on the patients' outcomes, NLR cutoff value classificat
ISSN:1008-9292