Idiopathic Vitritis after Boston Type 1 Keratoprosthesis Implantation: Incidence, Risk Factors and Outcomes in a Multicentric Cohort

To determine incidence, risks factors for, and outcomes of idiopathic vitritis (IV) after Boston type 1 keratoprosthesis (KPro) implantation. Retrospective, consecutive case series. Risk factors were analyzed between IV group and No IV group. IV occurred in 32/350 procedures (9.1%), for an average i...

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Bibliographic Details
Published in:Ocular immunology and inflammation 2022-05, Vol.30 (4), p.769-775
Main Authors: Bonnet, Clemence, Chehaibou, Ismael, Ghaffari, Reza, Jackson, Nicholas J., Bostan, Cristina, Hubschman, Jean-Pierre, Harissi-Dagher, Mona, Aldave, Anthony J.
Format: Article
Language:English
Subjects:
Boston type 1 keratoprosthesis
cornea
corneal melt
idiopathic vitritis
infectious keratitis
retinal detachment
risk factor
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Summary:To determine incidence, risks factors for, and outcomes of idiopathic vitritis (IV) after Boston type 1 keratoprosthesis (KPro) implantation. Retrospective, consecutive case series. Risk factors were analyzed between IV group and No IV group. IV occurred in 32/350 procedures (9.1%), for an average incidence of 0.02 cases per procedure-year. Presumed infectious keratitis was the only risk factor identified (HR = 7.65) Corneal necrosis and retinal detachment occurred significantly more frequently in IV group (all P 20/200 was significantly lower in IV group (P = .01), as was the KPro retention rate (HR = 0.26). IV is associated with infectious keratitis, indicating that the vitritis may not be a sterile process. The increased incidence of subsequent complications leads to significantly decreased visual acuity and KPro retention in affected eyes.
ISSN:0927-3948
1744-5078
DOI:10.1080/09273948.2020.1826541