Synthesis and potent antimicrobial activity of CoFe 2 O 4 nanoparticles under visible light

• Published in: Heliyon 2020-10, Vol.6 (10), p.e05058
• Main Authors: Gheidari, Davood, Mehrdad, Morteza, Maleki, Saloomeh, Hosseini, Samanesadat
• Format: Article
• Language: English
• ISSN: 2405-8440; 2405-8440

The nanoparticles of Cobalt ferrite are synthesized using polyethylene glycol as a solvent by the solvothermal method in a surfactant-free condition. Nanoparticles that were synthesized were determined by using various techniques such as Diffuse Reflection Spectroscopy (DRS), X-Ray Diffraction (XRD), Scanning Electron Microscope (SEM), and Energy Dispersive X-ray spectroscopy (EDAX). The Scanning electron microscope confirmed the range of spherical nanoparticles in the size of 20-33 nm.An excellent match was observed between the calculated particles size in the X-ray diffraction and electron microscopes results. Furthermore, their antimicrobial efficacy was determined by MIC, MBC, IC50 and disc diffusion method on Gram-negative ( and ) and Gram-positive ( ) bacteria. The results indicated an acceptable bacteriostatic and bactericidal effects of this nanoparticles. Additionally, it was seen that by the increase in the concentration of nanoparticles, their antimicrobial property would increase. In recent years, antibacterial materials have found a special place to avoid the overuse of antibiotics. In this study, the antibacterial effects of CoFe O nanoparticles on were investigated due to their importance as human pathogens in nosocomial infection. In this study, the antibacterial effects of CoFe O nanoparticles such as MIC, MBC, IC50, and disc diffusion method were examined. According to the results, CoFe O nanoparticles exhibited potent antibacterial activity against the bacteria that were examined, especially . The MBC (Minimum Bactericidal Concentration) of CoFe O nanoparticle on , , , was between 0.12-0.48 mg/ml and MIC (Minimum Inhibition Concentration) on these bacteria detected between 0.06-0.24 mg/ml. The least IC50 determined for with a concentration of 0.061 mg/ml. and identified as the most resistant and sensitive bacteria in the disc diffusion method, respectively.