A longitudinal analysis of the relationships between depression, fatigue, and pain in patients with heart failure

Depression, pain, and fatigue are common and bothersome symptoms in heart failure, a serious illness in older adults. Understanding longitudinal pathways among depression, pain, and fatigue in heart failure could inform treatment and improve quality of life. We completed secondary, longitudinal data...

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Bibliographic Details
Published in:Aging & mental health 2021-12, Vol.25 (12), p.2272-2278
Main Authors: Sheffler, Julia L., Schmiege, Sarah J., Sussman, Joleen, Bekelman, David B.
Format: Article
Language:English
Subjects:
Adults
Aged
Congestive heart failure
Depression
Depression - epidemiology
Fatigue
Fatigue - epidemiology
Fatigue failure
Geriatric psychiatry
Heart failure
Heart Failure - complications
Heart Failure - epidemiology
Humans
Mental depression
Older people
Pain
Pain - epidemiology
Patients
Quality of Life
Symptoms
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Summary:Depression, pain, and fatigue are common and bothersome symptoms in heart failure, a serious illness in older adults. Understanding longitudinal pathways among depression, pain, and fatigue in heart failure could inform treatment and improve quality of life. We completed secondary, longitudinal data analyses of a sample of older adults with heart failure (baseline N = 317). Bootstrapped mediation was used to examine two longitudinal models of pain and depression, with fatigue at 6-months as the mediator. The outcome variables were 12-month pain and depression. Depressive symptoms were associated with new onset of pain symptoms; however, this association was mediated by fatigue. Pain was not associated with new depression or fatigue symptoms in this sample. In patients with heart-failure, worsening pain symptoms appear to be directly related to levels of depression and fatigue. These findings demonstrate that depression and fatigue may be key to reducing pain symptoms in this population.
ISSN:1360-7863
1364-6915
DOI:10.1080/13607863.2020.1855626