The present situation of colorectal cancer in Chile

Colorectal (CRC) is one of the most common types of cancer worldwide. Most tumors develop from an adenoma in a period of 10 to 15 years, but some may appear without previous adenomatous lesions. Seventy-five percent of colorectal cancers are sporadic, 20% have a family component (first or second-deg...

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Bibliographic Details
Published in:Revista medíca de Chile 2020-06, Vol.148 (6), p.858
Main Authors: Ríos, Juvenal A, Barake, M Francisca, Arce, María José, López-Köstner, Francisco, Labbe, Tomas P, Villena, Jessica, Becerra, Sergio
Format: Article
Language:Spanish
Subjects:
Adenoma
Chile - epidemiology
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - epidemiology
Colorectal Neoplasms - genetics
Genetic Predisposition to Disease
Humans
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Summary:Colorectal (CRC) is one of the most common types of cancer worldwide. Most tumors develop from an adenoma in a period of 10 to 15 years, but some may appear without previous adenomatous lesions. Seventy-five percent of colorectal cancers are sporadic, 20% have a family component (first or second-degree relatives with CRC) and 5% have a hereditary predisposition with a Mendelian pattern. The epidemiological evolution in the recent years in Chile has a worrisome evolution and the treatment costs of advanced stages are a burden for the healthcare system. We herein highlight the main Chilean medical and scientific contributions on the pathogenesis, early diagnosis, and treatment of CRC, which lead to its better understanding, and therefore better management, based on local evidence.
ISSN:0717-6163