Two new polycyclic polyprenylated acylphloroglucinols derivatives from Hypericum acmosepalum

Polycyclic polyprenylated acylphloroglucinols (PPAPs) were mainly obtained from the plants of genus of Guttiferae family, and possessed intriguing chemical structures and appealing biological activities. Two new PPAPs derivatives, hyperacmosin C ( ) and hyperacmosin D ( ) were isolated from . Their...

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Published in:Journal of asian natural products research 2021-02, p.1
Main Authors: Suo, Xin-Yue, Shi, Meng-Jiao, Dang, Jun, Yue, Hui-Lan, Tao, Yan-Duo, Zhen, Bo, Wang, Jia-Jia, Wang, Xue, Sun, Hao-Ran, Sun, Hua, Qiang, Gui-Fen, Ji, Teng-Fei, Liu, Bo
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container_title Journal of asian natural products research
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creator Suo, Xin-Yue
Shi, Meng-Jiao
Dang, Jun
Yue, Hui-Lan
Tao, Yan-Duo
Zhen, Bo
Wang, Jia-Jia
Wang, Xue
Sun, Hao-Ran
Sun, Hua
Qiang, Gui-Fen
Ji, Teng-Fei
Liu, Bo
description Polycyclic polyprenylated acylphloroglucinols (PPAPs) were mainly obtained from the plants of genus of Guttiferae family, and possessed intriguing chemical structures and appealing biological activities. Two new PPAPs derivatives, hyperacmosin C ( ) and hyperacmosin D ( ) were isolated from . Their structures were established by NMR, HREIMS, and experimental electronic circular dichroism spectra. Besides, compound showed significant hepatoprotective activity at 10 µM against paracetamol-induced HepG2 cell damage and compound could moderately increase the relative glucose consumption.
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title Two new polycyclic polyprenylated acylphloroglucinols derivatives from Hypericum acmosepalum
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