A new diphenyl ether from Parmotrema indicum Hale growing in Vietnam

Chemical investigation of the lichen Parmotrema indicum Hale led to the isolation of one new diphenyl ether, parmetherine D (1), along with eight known compounds (2-9). The structures were determined by analysis of MS and NMR data and by comparison with the literature. Compounds 1, 2, and 7 were eva...

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Bibliographic Details
Published in:Natural product research 2022-10, Vol.36 (19), p.4879-4885
Main Authors: Do, Thanh-Hung, Nguyen, Thanh-Trung, Dao, Thi-Bich-Ngoc, Vo, Huu-Canh, Huynh, Bui-Linh-Chi, Nguyen, Thi-Anh-Tuyet, Mai, Dinh-Tri, Vo, Thi-Phi-Giao, Sichaem, Jirapast, Nguyen, Ngoc-Hong, Duong, Thuc-Huy
Format: Article
Language:English
Subjects:
Diphenyl ether
Glucosidase
Lichen
NMR
Nuclear magnetic resonance
parmetherine D
Parmotrema indicum Hale
α-Glucosidase
α-glucosidase inhibition
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Summary:Chemical investigation of the lichen Parmotrema indicum Hale led to the isolation of one new diphenyl ether, parmetherine D (1), along with eight known compounds (2-9). The structures were determined by analysis of MS and NMR data and by comparison with the literature. Compounds 1, 2, and 7 were evaluated for α-glucosidase inhibition. Only compound 1 exhibited significant inhibition.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2021.1907748