Similar therapeutic effects of 125 I seed radiotherapy and γ-ray radiotherapy on lacrimal gland adenoid cystic carcinoma

To evaluate the survival outcomes of patients with lacrimal gland adenoid cystic carcinoma who underwent eye-sparing surgery combined with I seed implantation radiotherapy or local external γ-ray radiotherapy. In this retrospective comparative case series, the clinical records of 27 primary and 8 re...

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Bibliographic Details
Published in:International journal of ophthalmology 2021, Vol.14 (4), p.547
Main Authors: Liu, Rui, Shi, Ji-Tong, Ge, Xin, Yang, Ben-Tao, Zhang, Hong, Zhang, Jing-Xue, Ma, Jian-Min
Format: Article
Language:English
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Summary:To evaluate the survival outcomes of patients with lacrimal gland adenoid cystic carcinoma who underwent eye-sparing surgery combined with I seed implantation radiotherapy or local external γ-ray radiotherapy. In this retrospective comparative case series, the clinical records of 27 primary and 8 recurrent patients were reviewed. Univariate and multivariate analyses were used to identify risk factors associated with distant metastasis (DM), and the overall survival (OS) after the initial surgery was analyzed. The median follow-up after radiotherapy was 36mo (range 6-120mo). At the last follow-up after radiotherapy, 26 (74.3%) patients had no evidence of disease, 7 (20%) patients had DM, 2 (5.9%) patients died of DM, and 1 patient with DM was lost to follow-up. Univariate analyses showed that duration of symptoms, bone destruction, T stage classification, and wide excision surgery were risk factors influencing DM (
ISSN:2222-3959
DOI:10.18240/ijo.2021.04.11